Medical graphic illustrating the complex physiological connections between type 2 diabetes and Alzheimer’s disease. The visual maps key mechanisms—such as insulin resistance, inflammation, oxidative stress, and mitochondrial dysfunction—that link peripheral metabolic disorders to central nervous system pathology. Created for Cummings, J., Ortiz, A., Castellino, J., & Kinney, J. (2022) in Diabetes: Risk Factor and Translational Therapeutic Implications for Alzheimer’s Disease (European Journal of Neuroscience, 56[9], 5727–5757).
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